Pub. Date : 2021
PMID : 33603947
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Propionibacterium acnes Accelerates Intervertebral Disc Degeneration by Inducing Pyroptosis of Nucleus Pulposus Cells via the ROS-NLRP3 Pathway. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
2 | Therefore, P. acnes induces NPC pyroptosis via the ROS-NLRP3 signaling pathway, and the pyroptotic NPCs cause an IVD degeneration cascade. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |