Title : Use of Real-World Data and Pharmacometric Modeling in Support of Lacosamide Dosing in Pediatric Patients Under 4 Years of Age.

Pub. Date : 2021 Jul

PMID : 33599301






1 Functional Relationships(s)
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1 A covariate analysis for age, sex, race, and co-administration of other antiepileptic drugs identified phenobarbital and felbamate to significantly increase lacosamide clearance (1.71 and 1.46-fold, respectively). Phenobarbital renin binding protein Homo sapiens