Title : The HSP90 inhibitor RGRN-305 exhibits strong immunomodulatory effects in human keratinocytes.

Pub. Date : 2021 Jun

PMID : 33583094






1 Functional Relationships(s)
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1 Interestingly, when keratinocytes were stimulated with a TLR3 agonist, RGRN-305 also demonstrated potent immunomodulatory effects, significantly inhibiting poly(I:C)-induced expression of the proinflammatory genes TNFalpha, IL1B, IL6, and IL23A. Poly I-C interleukin 6 Homo sapiens