Title : Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation.

Pub. Date : 2021 Apr 5

PMID : 33582578






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Respective compounds BS-10 and BS-22 inhibited AChE-induced Abeta1-42 aggregation in thioflavin T-assay at 10 muM and 20 muM, but BS-10 at 10 muM and 20 muM concentrations are found more potent than BS-22. thioflavin T acetylcholinesterase (Cartwright blood group) Homo sapiens