Title : Synthesis of imidazole-pyrazole conjugates bearing aryl spacer and exploring their enzyme inhibition potentials.

Pub. Date : 2021 Mar

PMID : 33581666






1 Functional Relationships(s)
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1 Compound 6k was the most potent alpha-glucosidase inhibitor with IC50 = 54.25 +- 0.67 microM as compared to reference drug acarbose (IC50 = 375.82 +- 1.76 microM). Acarbose sucrase-isomaltase Homo sapiens