Title : Acetylcholinesterase activity and thyroid hormone levels in Ecuadorian adolescents living in agricultural settings where organophosphate pesticides are used.

Pub. Date : 2021 Apr

PMID : 33581413






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1 Acetylcholinesterase activity and thyroid hormone levels in Ecuadorian adolescents living in agricultural settings where organophosphate pesticides are used. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens
2 BACKGROUND: Organophosphates are frequently applied insecticides that inhibit acetylcholinesterase (AChE) activity resulting in cholinergic overstimulation. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens
3 BACKGROUND: Organophosphates are frequently applied insecticides that inhibit acetylcholinesterase (AChE) activity resulting in cholinergic overstimulation. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens
4 We aimed to test the associations between AChE activity, a physiological marker of organophosphate exposure, and thyroid function in adolescents. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens
5 Lower AChE activity, indicating greater organophosphate exposure, was marginally associated with greater fT4 concentrations (difference per SD decrease in AChE activity (beta) = 0.03 ng/dL, [90% CI: 0.00, 0.06]) but not with TSH (beta = -0.01 muIU/ml, [-0.38, 0.36]). Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens