Title : Protection of nuclear DNA by lifespan-extending compounds in the yeast Saccharomyces cerevisiae.

Pub. Date : 2021 Jan-Jun

PMID : 33578051






1 Functional Relationships(s)
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1 We found that rapamycin and spermidine were able to decrease the spontaneous mutation rate at the CAN1 locus, whereas dinitrophenol, metformin, and resveratrol were able to protect yeast against CAN1 mutations induced by ethyl methanesulfonate (EMS). Ethyl Methanesulfonate arginine permease CAN1 Saccharomyces cerevisiae S288C