Pub. Date : 2020
PMID : 33574796
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In human seminoma cell line, while 17beta-estradiol (E2) inhibits in vitro cell proliferation through an ERbeta-dependent mechanism, an impermeable E2 conjugate (E2 coupled to BSA), in vitro cell proliferation is stimulated by activating ERK1/2 and protein kinase A through a membrane GPCR that we further identified as GPER/GPR30. | Estradiol | mitogen-activated protein kinase 3 | Homo sapiens |
| 2 | In human seminoma cell line, while 17beta-estradiol (E2) inhibits in vitro cell proliferation through an ERbeta-dependent mechanism, an impermeable E2 conjugate (E2 coupled to BSA), in vitro cell proliferation is stimulated by activating ERK1/2 and protein kinase A through a membrane GPCR that we further identified as GPER/GPR30. | Estradiol | mitogen-activated protein kinase 3 | Homo sapiens |