Title : Deletion or inhibition of SphK1 mitigates fulminant hepatic failure by suppressing TNFα-dependent inflammation and apoptosis.

Pub. Date : 2021 Mar

PMID : 33566377






1 Functional Relationships(s)
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1 Whereas GalN/LPS treatment-induced hepatic activation of NF-kappaB and JNK in wild-type and SphK2-/- mice, these signaling pathways were reduced in SphK1-/- mice. Galactosamine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus