Title : Electrochemically Enabled One-Pot Multistep Synthesis of C19 Androgen Steroids.

Pub. Date : 2021 Apr 1

PMID : 33556193






2 Functional Relationships(s)
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1 A reagent and catalyst free protocol for the removal of the C17 side-chain of corticosteroids via anodic oxidation has been developed, enabling several one-pot, multistep procedures for the synthesis of androgen steroids. Steroids cytokine like 1 Homo sapiens
2 In addition, simultaneous anodic C17 side-chain cleavage and cathodic catalytic hydrogenation of a steroid has been demonstrated, rendering a convenient and highly atom economic procedure for the synthesis of saturated androgens. Steroids cytokine like 1 Homo sapiens