Title : Both Hypoxia-Inducible Factor 1 and MAPK Signaling Pathway Attenuate PI3K/AKT via Suppression of Reactive Oxygen Species in Human Pluripotent Stem Cells.

Pub. Date : 2020

PMID : 33553145






1 Functional Relationships(s)
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1 This inhibition of ROS initiated by MEK1/2-ERK1/2 may serve as a negative feedback loop from the MAPK pathway toward FGFR1 and PI3K/AKT activation. Reactive Oxygen Species mitogen-activated protein kinase 3 Homo sapiens