Title : Transporter Gene Regulation in Sandwich Cultured Human Hepatocytes Through the Activation of Constitutive Androstane Receptor (CAR) or Aryl Hydrocarbon Receptor (AhR).

Pub. Date : 2020

PMID : 33551819






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 As expected, CITCO, the direct activator, and PB, the indirect activator of CAR, induced CYP3A4 (31 and 40-fold), CYP2B6 (24 and 28-fold) and UGT1A1 (2.9 and 4.2-fold), respectively. Phenobarbital UDP glucuronosyltransferase family 1 member A1 Homo sapiens