Title : Calreticulin is important for the development of renal fibrosis and dysfunction in diabetic nephropathy.

Pub. Date : 2020 Nov

PMID : 33543033






1 Functional Relationships(s)
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1 Knockdown of CALR by siRNA in a human proximal tubular cell line (HK-2) showed reduced induction of soluble collagen when stimulated by TGF-beta or high glucose as compared to control cells, as well as a reduction in fibronectin and collagen IV transcript levels. Glucose calreticulin Homo sapiens