Title : Salicylate suppresses the oncogenic hyaluronan network in metastatic breast cancer cells.

Pub. Date : 2020 May

PMID : 33543028






1 Functional Relationships(s)
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1 The present study demonstrates that salicylate, a break down product of aspirin in vivo, alters the organization of hyaluronan matrices by affecting the expression levels of hyaluronan synthesizing (HAS1, 2, 3) and degrading (HYAL-1, -2) enzymes, and that of hyaluronan receptor CD44. Salicylates hyaluronan synthase 1 Homo sapiens