Pub. Date : 2021
PMID : 33523042
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Thus, in the present study, miRNA-mediated modulation of HK2 during ROS (H2O2)-induced cardiomyocyte apoptosis was investigated. | Hydrogen Peroxide | hexokinase 2 | Homo sapiens |
| 2 | First, the expression of HK2 in cardiomyocytes exposed to H2O2 was evaluated. | Hydrogen Peroxide | hexokinase 2 | Homo sapiens |
| 3 | H2O2 (500muM) induced cardiomyocyte apoptosis and it also decreased the mitochondrial expression of HK2. | Hydrogen Peroxide | hexokinase 2 | Homo sapiens |
| 4 | Delivery of anti-miR-181a significantly abrogated the H2O2-induced suppression of HK2 expression and subsequent disruption of mitochondrial membrane potential, improving the survival of cardiomyocytes exposed to H2O2. | Hydrogen Peroxide | hexokinase 2 | Homo sapiens |