Title : Physiologically-Based Pharmacokinetic-Pharmacodynamics Model Characterizing CYP2C19 Polymorphisms to Predict Clopidogrel Pharmacokinetics and Its Anti-Platelet Aggregation Effect Following Oral Administration to Coronary Artery Disease Patients With or Without Diabetes.

Pub. Date : 2020

PMID : 33519456






1 Functional Relationships(s)
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1 Clopidogrel resistance by DM was the integrated effects of altered K t,i, CYP2C19, CYP3A4, CES1 and k irre. Clopidogrel cytochrome P450 family 3 subfamily A member 4 Homo sapiens