Title : Insights Into the Impacts of BRCA Mutations on Clinicopathology and Management of Early-Onset Triple-Negative Breast Cancer.

Pub. Date : 2020

PMID : 33505905






2 Functional Relationships(s)
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1 Compared with BRCA wild patients, BRCA mutated patients had a higher likelihood of receiving anthracyclines and taxane-based combination chemotherapy (P = 0.04) and tend to be lower tumor burden (P =0.01). taxane BRCA1 DNA repair associated Homo sapiens
2 Conclusions: These results suggest that eTNBC patients with BRCA mutations are prone to better OS and BCSS, which might be largely attributed to more benefit from anthracyclines and taxane-based chemotherapy. taxane BRCA1 DNA repair associated Homo sapiens