Title : [Progranulin (PGRN) promotes invasion and migration of mouse breast cancer 4T1 cells by promoting epithelial-mesenchymal transition of cancer cells and activating ERK1/2 pathway].

Pub. Date : 2021 Feb

PMID : 33504418






1 Functional Relationships(s)
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1 After treated with 1 mug/mL PGRN and ERK1/2 signaling pathway inhibitor U0126 (10 mumol/L) simultaneously, the migration and invasion ability of 4T1 cells and the changes in the expression of E-cadherin, vimentin and p-ERK proteins were detected again. U 0126 mitogen-activated protein kinase 3 Mus musculus