Title : Downregulation of miR‑409‑3p suppresses LPS‑induced inflammation in human bronchial epithelial cells through SOCS3/JAK1/STAT3 signaling: The implication for bronchopneumonia.

Pub. Date : 2021 Mar

PMID : 33495807






1 Functional Relationships(s)
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1 The inhibition of SOCS3 significantly activated JAK1/STAT3 signaling, as well as enhancing the levels of TNF-alpha, IL-6 and IL-1beta, and promoting apoptosis, which was reversed by the JAK1 inhibitor Tofacitinib. tofacitinib interleukin 6 Homo sapiens