Title : Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy.

Pub. Date : 2021 Jan 25

PMID : 33495450






1 Functional Relationships(s)
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1 CRISPR/Cas9-mediated MALAT1 promoter deletion in BT-549 TNBC model enhanced sensitivity to paclitaxel and doxorubicin, suggesting a role for MALAT1 in conferring resistance. Doxorubicin metastasis associated lung adenocarcinoma transcript 1 Homo sapiens