Pub. Date : 2021 Jan
PMID : 33489855
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment of cells with the COX-2 selective inhibitor celecoxib induced cell death of AGS FR cells in a time- and concentration-dependent manner. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | This apoptotic induction was strongly supported by the expression profiles of apoptosis- and survival-associated proteins in response to celecoxib; pro-apoptotic cellular proteins increased while expressions of COX-2 and p-Akt were downregulated in a concentration-dependent manner. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 3 | Based on the data that downregulation of COX-2 was correlated with the concentrations of celecoxib, COX-2 may play a key role in celecoxib-induced cell death of AGS FR cells. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 4 | Based on the data that downregulation of COX-2 was correlated with the concentrations of celecoxib, COX-2 may play a key role in celecoxib-induced cell death of AGS FR cells. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 5 | Based on the data that downregulation of COX-2 was correlated with the concentrations of celecoxib, COX-2 may play a key role in celecoxib-induced cell death of AGS FR cells. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 6 | Based on the data that downregulation of COX-2 was correlated with the concentrations of celecoxib, COX-2 may play a key role in celecoxib-induced cell death of AGS FR cells. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |