Title : Biphenylurea/thiourea derivatives tagged with heteroarylsulfonamide motifs as novel VEGFR2 inhibitors; Design, synthesis and anti-angiogenic activity.

Pub. Date : 2021 Feb

PMID : 33485105






1 Functional Relationships(s)
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1 All compounds significantly inhibited VEGF stimulated migration of HUVECs at 10 microM dose with (3a, 3e, 3g, 3h and 3l) showing better or comparable inhibitory activities to that of sorafenib. Tritium vascular endothelial growth factor A Homo sapiens