Pub. Date : 2021 Jan 18
PMID : 33462182
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway. | Arsenic Trioxide | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Moreover, ATO decreased the p-AKT and p-mTOR in the PI3K/AKT/mTOR signaling pathway, thus inducing autophagy. | Arsenic Trioxide | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | Moreover, ATO decreased the p-AKT and p-mTOR in the PI3K/AKT/mTOR signaling pathway, thus inducing autophagy. | Arsenic Trioxide | thymoma viral proto-oncogene 1 | Mus musculus |
| 4 | In summary, our data indicated that ATO promoted ROS induction, which resulted in nuclear translocation of TFEB and inhibition of the PI3K/AKT/mTOR pathway. | Arsenic Trioxide | thymoma viral proto-oncogene 1 | Mus musculus |