Title : Thrombin inhibitor argatroban modulates bone marrow stromal cells behaviors and promotes osteogenesis through canonical Wnt signaling.

Pub. Date : 2021 Mar 15

PMID : 33460666






1 Functional Relationships(s)
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1 Interestingly, without affecting osteoclastogenesis, osteogenic differentiation was significantly induced by argatroban, which were shown by extracellular mineralization and upregulation of early osteoblastic differentiation markers, alkaline phosphatase, Osteocalcin, transcription factors RUNX2 and Osterix. argatroban bone gamma-carboxyglutamate protein 2 Mus musculus