Pub. Date : 1988 Feb
PMID : 3345272
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Plasma glutathione S-transferase concentration as a measure of hepatocellular integrity following a single general anaesthetic with halothane, enflurane or isoflurane. | Enflurane | glutathione S-transferase kappa 1 | Homo sapiens |
| 2 | The plasma concentration of hepatic glutathione S-transferase (GST) was measured in matched groups of patients who received halothane, enflurane or isoflurane anaesthesia for elective minor surgery. | Enflurane | glutathione S-transferase kappa 1 | Homo sapiens |
| 3 | The GST concentrations increased significantly at 3 h after anaesthesia in patients who received halothane or enflurane, but not in patients who were given isoflurane. | Enflurane | glutathione S-transferase kappa 1 | Homo sapiens |
| 4 | A secondary increase in GST concentration, at 24 h, was seen in a small number of individuals who received halothane or enflurane. | Enflurane | glutathione S-transferase kappa 1 | Homo sapiens |
| 5 | Abnormal GST concentrations were found in 50% of patients following halothane anaesthesia, 20% following enflurane and 11% after isoflurane. | Enflurane | glutathione S-transferase kappa 1 | Homo sapiens |
| 6 | The small but significant increases in GST concentrations in patients receiving halothane or enflurane suggests an impairment of hepatocellular integrity following the administration of these anaesthetics. | Enflurane | glutathione S-transferase kappa 1 | Homo sapiens |