Title : Inhibition of S-adenosyl-L-homocysteine hydrolase alleviates alloimmune response by down-regulating CD4+ T-cell activation in a mouse heart transplantation model.

Pub. Date : 2020 Dec

PMID : 33437781






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 S-adenosyl-L-homocysteine hydrolase (SAHH) inhibitors prevent the feedback of transmethylation reactions by S-adenosyl-L-homocysteine (SAH) accumulation, a competitive antagonist of S-adenosylmethionine (SAM)-dependent methyltransferases. S-Adenosylhomocysteine S-adenosylhomocysteine hydrolase Mus musculus