Pub. Date : 2021 Mar
PMID : 33433355
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here we analyze the antifibrotic mechanisms of Halofuginone (HF), a drug reportedly able to inhibit the TGF-beta1-Smad3 pathway and to attenuate collagen synthesis, in an in-vitro keloid model using patient-derived Keloid Fibroblasts (KFs) isolated from fibrotic tissue collected during the "Scar Wars" clinical study (NCT NCT03312166). | halofuginone | SMAD family member 3 | Homo sapiens |