Pub. Date : 2020
PMID : 33424864
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Distinct Molecular Mechanisms Underlying Potassium Efflux for NLRP3 Inflammasome Activation. | Potassium | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Potassium efflux has been reported to be essential for NLRP3 inflammasome activation by structurally diverse pathogen-associated molecular patterns (PAMPs) or danger-associated molecular patterns (DAMPs). | Potassium | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | Thus, the molecular mechanisms underlying potassium efflux to activate NLRP3 inflammasome are under extensive investigation. | Potassium | NLR family pyrin domain containing 3 | Homo sapiens |
| 4 | Here, we review current knowledge about the distinction channels or pore-forming proteins underlying potassium efflux for NLRP3 inflammasome activation with canonical/non-canonical signaling or following caspase-8 induced pyroptosis. | Potassium | NLR family pyrin domain containing 3 | Homo sapiens |