Title : A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability.

Pub. Date : 2021 Jan 8

PMID : 33420359






1 Functional Relationships(s)
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1 Taken together, these preclinical results unveil the mode of action of AG1529 on TRPV1 channels and substantiate the tenet that this capsaicinoid-based soft drug is a promising candidate for drug development as a topical anti-pruritic and anti-inflammatory medication. Capsaicin transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus