Pub. Date : 2021 Feb
PMID : 33414501
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cocaine-induced locomotor stimulation involves autophagic degradation of the dopamine transporter. | Cocaine | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | Mus musculus |
| 2 | This action is thought to reflect binding of cocaine to the dopamine transporter (DAT) to inhibit its function. | Cocaine | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | Mus musculus |
| 3 | This action is thought to reflect binding of cocaine to the dopamine transporter (DAT) to inhibit its function. | Cocaine | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | Mus musculus |
| 4 | However, cocaine is a relatively weak inhibitor of DAT, and many DAT inhibitors do not share the behavioral actions of cocaine. | Cocaine | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | Mus musculus |
| 5 | Our findings indicate that autophagic degradation of DAT modulates behavioral actions of cocaine. | Cocaine | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | Mus musculus |