Title : Overexpression of long noncoding RNA ANRIL inhibits phenotypic switching of vascular smooth muscle cells to prevent atherosclerotic plaque development in vivo.

Pub. Date : 2020 Dec 19

PMID : 33411680






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In vivo, administration of metformin increased the levels of lncRNA-ANRIL, suppressed VSMC phenotypic switching, and prevented the development of atherosclerotic plaque in Apoe-/- mice fed with western diet. Metformin apolipoprotein E Mus musculus
2 These protective effects of metformin were abolished by infecting Apoe-/- mice with adenovirus expressing lncRNA-ANRIL shRNA. Metformin apolipoprotein E Mus musculus