Title : Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway.

Pub. Date : 2021 Jan 29

PMID : 33393627






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cyclophilin A (CypA), a member of the immunophilin family, is secreted in response to ROS. Reactive Oxygen Species peptidylprolyl isomerase A Homo sapiens
2 Cyclophilin A (CypA), a member of the immunophilin family, is secreted in response to ROS. Reactive Oxygen Species peptidylprolyl isomerase A Homo sapiens
3 Our results demonstrated that hCypA substantially promoted cell viability, superoxide dismutase (SOD), glutathione (GSH), and GSH peroxidase (GSH-Px) activities, and attenuated ROS and malondialdehyde (MDA) production in H2O2-induced A549 cells. Reactive Oxygen Species peptidylprolyl isomerase A Homo sapiens