Title : [Anti-oxidants in astrocytes as target of neuroprotection for Parkinson's disease].

Pub. Date : 2021

PMID : 33390474






1 Functional Relationships(s)
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1 We previously revealed that several antiepileptic drugs, serotonin 5-HT1A receptor agonists, plant-derived chemicals (phytochemicals) increased xCT expression, Nrf2 activation, GSH or MT expression and release in/from astrocytes, and exerted a neuroprotective effect against dopaminergic neurodegeneration in Parkinson"s disease model. Serotonin 5-hydroxytryptamine receptor 1A Homo sapiens