Pub. Date : 2021 Feb
PMID : 33387788
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dexamethasone inhibits SARS-CoV-2 spike pseudotyped virus viropexis by binding to ACE2. | Dexamethasone | angiotensin converting enzyme 2 | Homo sapiens |
| 2 | Molecular docking results revealed that DEX occupied with active binding site of ACE2 of SARS-CoV-2 spike protein. | Dexamethasone | angiotensin converting enzyme 2 | Homo sapiens |
| 3 | Surface plasmon resonance (SPR) results showed that KD value between DEX and ACE2 was (9.03 +- 0.78) e-6 M. Cell membrane chromatography (CMC) results uncovered that DEX had a chromatographic retention. | Dexamethasone | angiotensin converting enzyme 2 | Homo sapiens |
| 4 | Surface plasmon resonance (SPR) results showed that KD value between DEX and ACE2 was (9.03 +- 0.78) e-6 M. Cell membrane chromatography (CMC) results uncovered that DEX had a chromatographic retention. | Dexamethasone | angiotensin converting enzyme 2 | Homo sapiens |
| 5 | DEX was found out to inhibiting the viropexis into ACE2h cells using SARS-CoV-2 spike pseudotyped virus. | Dexamethasone | angiotensin converting enzyme 2 | Homo sapiens |
| 6 | Therefore, DEX inhibits the entrance of SARS-CoV-2 spike pseudotyped virus into cell by binding to ACE2. | Dexamethasone | angiotensin converting enzyme 2 | Homo sapiens |