Title : Suppression of Urokinase-Type Plasminogen Activator Receptor by Docosahexaenoic Acid Mediated by Heme Oxygenase-1 in 12-O-Tetradecanoylphorbol-13-Acetate-Induced Human Endothelial Cells.

Pub. Date : 2020

PMID : 33381031






5 Functional Relationships(s)
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1 Suppression of Urokinase-Type Plasminogen Activator Receptor by Docosahexaenoic Acid Mediated by Heme Oxygenase-1 in 12-O-Tetradecanoylphorbol-13-Acetate-Induced Human Endothelial Cells. Tetradecanoylphorbol Acetate heme oxygenase 1 Homo sapiens
2 In addition, DHA-induced inhibition of uPAR expression and cell invasion in TPA-stimulated cells was reversed by si-HO-1 RNA. Tetradecanoylphorbol Acetate heme oxygenase 1 Homo sapiens
3 Induction of HO-1 by ferric protoporphyrin IX (FePP) inhibited TPA-induced uPAR expression, and this effect was abolished by treatment with the HO-1 inhibitor tin protoporphyrin IX (SnPP). Tetradecanoylphorbol Acetate heme oxygenase 1 Homo sapiens
4 Induction of HO-1 by ferric protoporphyrin IX (FePP) inhibited TPA-induced uPAR expression, and this effect was abolished by treatment with the HO-1 inhibitor tin protoporphyrin IX (SnPP). Tetradecanoylphorbol Acetate heme oxygenase 1 Homo sapiens
5 Additionally, carbon monoxide, an HO-1 product, attenuated TPA-induced uPAR expression and cell invasion. Tetradecanoylphorbol Acetate heme oxygenase 1 Homo sapiens