Pub. Date : 2021 Mar
PMID : 33376814
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | : Regulation of HCO3 -Transport and extracellular pH by CFTR. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 2 | Expression of functional CFTR may normally regulate extracellular pH via control of bicarbonate efflux. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 3 | Reports also suggest that the CFTR may be a Cl-/HCO3- exchanger. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 4 | We compared evidentiary support of four possible models of CFTR"s role in the transport of bicarbonate: 1) CFTR as a Cl-channel that permits bicarbonate conductance, 2) CFTR as an anion Cl-/HCO3- exchanger (AE), 3.) | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 5 | We compared evidentiary support of four possible models of CFTR"s role in the transport of bicarbonate: 1) CFTR as a Cl-channel that permits bicarbonate conductance, 2) CFTR as an anion Cl-/HCO3- exchanger (AE), 3.) | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 6 | We compared evidentiary support of four possible models of CFTR"s role in the transport of bicarbonate: 1) CFTR as a Cl-channel that permits bicarbonate conductance, 2) CFTR as an anion Cl-/HCO3- exchanger (AE), 3.) | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 7 | We compared evidentiary support of four possible models of CFTR"s role in the transport of bicarbonate: 1) CFTR as a Cl-channel that permits bicarbonate conductance, 2) CFTR as an anion Cl-/HCO3- exchanger (AE), 3.) | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 8 | We compared evidentiary support of four possible models of CFTR"s role in the transport of bicarbonate: 1) CFTR as a Cl-channel that permits bicarbonate conductance, 2) CFTR as an anion Cl-/HCO3- exchanger (AE), 3.) | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 9 | We compared evidentiary support of four possible models of CFTR"s role in the transport of bicarbonate: 1) CFTR as a Cl-channel that permits bicarbonate conductance, 2) CFTR as an anion Cl-/HCO3- exchanger (AE), 3.) | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 10 | We compared evidentiary support of four possible models of CFTR"s role in the transport of bicarbonate: 1) CFTR as a Cl-channel that permits bicarbonate conductance, 2) CFTR as an anion Cl-/HCO3- exchanger (AE), 3.) | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 11 | CFTR as a Cl-channel that allows for transport of bicarbonate and regulates an independent AE. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 12 | This data, as well as that published by others, suggest that while CFTR may support and regulate bicarbonate flux it is unlikely it directly performs Cl-/HCO3- anion exchange. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |