Title : Drug Delivery Strategies to Overcome the Blood-Brain Barrier (BBB).

Pub. Date : 2020 Dec 25

PMID : 33367937






1 Functional Relationships(s)
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1 While the concept works to some extent, a lot of challenges have been encountered in terms of obtaining efficient inhibition while avoiding adverse effects.Some CNS drug compounds enter the brain via nutrient transport proteins, an example is the levodopa, a prodrug of Dopamine, which crosses the BBB via the large neutral amino acid transporter LAT1. Levodopa solute carrier family 7 member 5 Homo sapiens