Title : Intestinal regulatory T cell induction by β-elemene alleviates the formation of fat tissue-related inflammation.

Pub. Date : 2021 Jan 22

PMID : 33364577






2 Functional Relationships(s)
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1 Oral administration of beta-elemene, contained in various foodstuffs, downregulated expressions of inflammatory cytokines and increased Foxp3+CD4+ T cells in adipose tissue of obese mice. beta-elemene forkhead box P3 Mus musculus
2 Instead, beta-elemene increased Foxp3+CD4+ T cell population enhancing gene expressions of transforming growth factor beta 1, retinaldehyde dehydrogenase 2, integrin alphavbeta8, and interleukin-10 in intestinal dendritic cells (DCs) in vivo and in vitro. beta-elemene forkhead box P3 Mus musculus