Pub. Date : 2020
PMID : 33362238
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acadesine, an analog of AMP and an AMP-activated protein kinase (AMPK) activator, has been shown to have cytoprotective effects in human clinical trials as well as having anti-inflammatory and anti-vascular exudative effects in animals. | acadesine | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 2 | Acadesine, an analog of AMP and an AMP-activated protein kinase (AMPK) activator, has been shown to have cytoprotective effects in human clinical trials as well as having anti-inflammatory and anti-vascular exudative effects in animals. | acadesine | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 3 | CONCLUSIONS: Our results suggest that acadesine suppresses TNF-alpha induced C3, likely through an AMPK-independent pathway, and could have potential use in complement over activation diseases. | acadesine | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |