Title : Kinetic Effects of β,γ-Modified Deoxynucleoside 5'-Triphosphate Analogues on RNA-Catalyzed Polymerization of DNA.

Pub. Date : 2021 Jan 12

PMID : 33356161






1 Functional Relationships(s)
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1 The apparent rate constant (kpol) of the polymerase ribozyme was determined for analogues of dGTP and dCTP that span a broad range of acidities for the leaving group, ranging from 7.8 for the CF2-bisphosphonate to 11.6 for the CHCH3-bisphosphonate. deoxyguanosine triphosphate ATPase H+ transporting accessory protein 1 Homo sapiens