Title : Evaluation of Tissue Stem Cell-Derived Human Intestinal Organoids, a Physiologically Relevant Model to Evaluate Cytochrome P450 Induction in Gut.

Pub. Date : 2021 Mar

PMID : 33355212






1 Functional Relationships(s)
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1 Omeprazole failed to induce CYP1A2 mRNA, but induced CYP1A1 mRNA (up to 7.7-fold and 15-fold in ileal and colon organoids, respectively, n = 4 experiments). Omeprazole cytochrome P450 family 1 subfamily A member 1 Homo sapiens