Pub. Date : 2021 Mar 5
PMID : 33345849
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Proliferation assay and apoptosis assay were applied and proved that IL-6 enhances the chemoresistance of OvCa cells against cisplatin through the upregulation of HIF-1alpha via the STAT3 signaling in vitro. | Cisplatin | interleukin 6 | Homo sapiens |
| 2 | The In vivo studies confirmed the effect of IL-6 in increasing the chemoresistance of OvCa cells against cisplatin through the IL-6/STAT3/HIF-1alpha loop in the animal models. | Cisplatin | interleukin 6 | Homo sapiens |