Title : The RabGEF ALS2 is a hypoxia inducible target associated with the acquisition of aggressive traits in tumor cells.

Pub. Date : 2020 Dec 18

PMID : 33339852






1 Functional Relationships(s)
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1 Here, we identified ALS2, a guanine nucleotide exchange factor that is upregulated in cancer, as responsible for increased Rab5-GTP loading, cell migration and metastasis in hypoxia. Guanine Nucleotides RAB5A, member RAS oncogene family Homo sapiens