Pub. Date : 2021 Feb 5
PMID : 33338868
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Conjugation of tacrine with genipin derivative not only enhances effects on AChE but also leads to autophagy against Alzheimer"s disease. | Tacrine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | Compound 8-7 was confirmed as the most active AChE inhibitor with IC50 value of 5.8 +- 1.4 nM, which was 7.72-fold stronger than tacrine. | Tacrine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |