Title : Enzyme-enzyme interactions as modulators of the metabolic flux through the citric acid cycle.

Pub. Date : 1987

PMID : 3332992






1 Functional Relationships(s)
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1 From affinity chromatographic experiments, we have shown that the enzymes of the citric acid cycle and the aspartate-malate shuttle are organized as one huge multi-enzyme complex, and a stoichiometric arrangement of fumarase/malate dehydrogenase/citrate synthase/aspartate aminotransferase has been postulated. malic acid citrate synthase Homo sapiens