Pub. Date : 2021 Feb
PMID : 33300068
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Neuroprotective effect of emodin against Alzheimer"s disease via Nrf2 signaling in U251 cells and APP/PS1 mice. | Emodin | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 2 | Compared with those after Abeta exposure alone, emodin ameliorated the dissipation of the mitochondrial membrane potential, inhibited the over-accumulation of reactive oxygen species, enhanced the expression levels of nuclear factor-erythroid-2-related factor 2 (Nrf2), haemeoxygenase-1, superoxide dismutase 1, Bcl-2 and catalase in addition to decreasing the expression levels of Bax. | Emodin | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 3 | Compared with those after Abeta exposure alone, emodin ameliorated the dissipation of the mitochondrial membrane potential, inhibited the over-accumulation of reactive oxygen species, enhanced the expression levels of nuclear factor-erythroid-2-related factor 2 (Nrf2), haemeoxygenase-1, superoxide dismutase 1, Bcl-2 and catalase in addition to decreasing the expression levels of Bax. | Emodin | NFE2 like bZIP transcription factor 2 | Homo sapiens |