Title : Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.

Pub. Date : 2021 Jan

PMID : 33296782






2 Functional Relationships(s)
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1 Pretreatment with an NF-kappaB inhibitor suppressed inflammation, improved cell permeability to FITC-dextran and increased Occludin and ZO-1 levels. fluorescein isothiocyanate dextran nuclear factor kappa B subunit 1 Homo sapiens
2 The effects induced by transfection with the miR-155 mimic, including elevated TNF-alpha and IL-6 levels, hyperpermeability to FITC-dextran and reduced ZO-1 and Occludin expression, were partly rescued by pretreatment with the NF-kappaB inhibitor. fluorescein isothiocyanate dextran nuclear factor kappa B subunit 1 Homo sapiens