Title : High n-3 fatty acids counteract hyperglycemia-induced insulin resistance in fat-1 mice via pre-adipocyte NLRP3 inflammasome inhibition.

Pub. Date : 2021 Jan 7

PMID : 33295913






1 Functional Relationships(s)
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1 Endogenous n-3 PUFAs in fat-1 mice were found to impair hyperglycemia or high glucose level-induced nucleotide-binding domain and leucine-rich repeat pyrin 3 domain (NLRP3) inflammasome activation and inhibit IL-1beta secretion in adipose tissues. Leucine NLR family, pyrin domain containing 3 Mus musculus