Title : MicroRNA-135a-5p Promotes the Functional Recovery of Spinal Cord Injury by Targeting SP1 and ROCK.

Pub. Date : 2020 Dec 4

PMID : 33294293






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 By establishing the H2O2-induced injury model, miR-135a-5p transfection was found to inhibit the apoptosis of PC12 cells by downregulating the SP1 gene, which subsequently induced downregulation of pro-apoptotic proteins (Bax, cleaved caspase-3) and upregulation of anti-apoptotic protein Bcl-2. Hydrogen Peroxide BCL2 associated X, apoptosis regulator Rattus norvegicus