Title : Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamics.

Pub. Date : 2021 Feb 1

PMID : 33285261






2 Functional Relationships(s)
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1 Here we show that SIRT3 is neuroprotective in Huntington"s disease (HD), a motor neurodegenerative disorder caused by an abnormal expansion of polyglutamines in the huntingtin protein (HTT). polyglutamine huntingtin Homo sapiens
2 Here we show that SIRT3 is neuroprotective in Huntington"s disease (HD), a motor neurodegenerative disorder caused by an abnormal expansion of polyglutamines in the huntingtin protein (HTT). polyglutamine huntingtin Homo sapiens